Small Bowel Adenocarcinoma: FOLFIRINOX vs. FOLFOX

We are studying two chemotherapy treatments for patients with locally advanced or metastatic small bowel adenocarcinoma. The goal is to find out which treatment helps patients live longer without their cancer worsening.

>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesInjectionGastroenterologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Calcium Levofolinate
Calcium levofolinate is a substance that helps protect healthy cells during some cancer treatments and restores folate levels.
Fluorouracil
Fluorouracil is a substance used to treat cancer by stopping the growth of cancer cells.
Irinotecan Hydrochloride Trihydrate
Irinotecan hydrochloride trihydrate is a chemotherapy agent used to treat several types of cancer, especially colorectal cancer.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier D Albi
Oncology
Albi, France
Centre Hospitalier Annecy Genevois
Hepatogastroenterology
Annecy, France
Centre Hospitalier D Auxerre
Oncology
Auxerre, France
Sponsor: Centre Hospitalier Universitaire De Dijon
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.