Liver Cancer (Hepatocellular Carcinoma)
Hepatocellular carcinoma (HCC) is a type of liver cancer that often occurs in people with chronic liver diseases, such as cirrhosis. It can lead to symptoms like weight loss, abdominal pain, and jaundice.
Solid Tumors: E7386 with Other Anticancer Drugs
We are studying the safety and effectiveness of E7386 combined with other anticancer treatments for patients with solid tumors. This trial aims to find the best dose and assess how well it works compared to standard therapies.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Colorectal Cancer
Colorectal cancer is a type of cancer that starts in the colon or rectum, often presenting with symptoms like changes in bowel habits, blood in stool, and abdominal discomfort.
Endometrial Cancer
Endometrial cancer is a cancer that begins in the lining of the uterus, commonly causing symptoms such as abnormal vaginal bleeding and pelvic pain.
Solid Tumors
Solid tumors are abnormal masses of tissue that can occur in various organs and can be benign or malignant. Symptoms vary widely depending on the tumor's location.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 18 and 75 years old?
- Do you have liver cancer (HCC) or another solid tumor that has no effective treatment?
- Are you currently pregnant or breastfeeding?
- Are you taking blood thinners like Warfarin, Eliquis, or Xarelto?
- Have you had major surgery in the past 3 months?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
E7386
(6s,9as)-8-((6-(3-(4-ethyl-1-piperazinyl)-1-azetidinyl)-2-pyridinyl)methyl)-6-((2-fluoro-4-hydroxyphenyl)methyl)hexahydro-4
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Abutrax
Abutrax
Adriacept Blasen-Instillations-Set
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Rigshospitalet
Department of Oncology
Copenhagen, Denmark
Odense University Hospital
Department of Oncology
Odense, Denmark
Institut De Cancerologie De L Ouest
Medical oncology
Avignon, France
Sponsor: Eisai Limited
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.