Solid Tumors: Genetically Modified T-Cell Therapy

We are studying a new treatment using modified T-cells from patients to target specific tumor markers in solid tumors. The trial will help us understand its safety and effectiveness, both alone and with another medication.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Opdivo
Opdivo is a cancer medicine that helps the immune system find and fight tumor cells.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Nivolumab
Nivolumab is a substance that helps the immune system recognize and attack certain cancers.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Ima203
Autologous T-Cells Transduced With The Lentiviral Lv-R11kea Encoding T-Cell Receptor Targeting Patient-Specific Tumor-Associated Antigens

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Opdualag

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Universitaetsklinikum Bonn AöR
Medizinische Klinik III, Abt. für Hämatologie, Onkologie und Rheumatologie
Bonn, Germany
Universitaetsklinikum Carl Gustav Carus Dresden an der Technischen Universitaet Dresden AöR
Early Clinical Trial Unit (NCT/UCC ECTU)
Dresden, Germany
University Medical Center Hamburg-Eppendorf
II. Medizinische Klinik
Hamburg, Germany

Sponsor: Immatics US Inc.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.