Solid Tumors: Valemetostat Tosylate with DXd ADCs

We are studying a new combination treatment for patients with solid tumors to evaluate its safety and effectiveness. This trial aims to find better options for managing cancer.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Datopotamab Deruxtecan
Datopotamab deruxtecan is an antibody-based substance that targets a protein called TROP2 to deliver chemotherapy directly to certain solid tumors.
Trastuzumab Deruxtecan
Trastuzumab deruxtecan is a targeted cancer treatment that attacks tumors with high HER2 protein levels.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Ds-8201a
Valemetostat Tosylate

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Institut De Cancerologie De L Ouest
Medical Oncology
Avignon, France
Centre Hospitalier Regional De Marseille
Centre d'Essais en Cancérologie de marseille (CEPCM - CLIPP)
Marseille, France
Institut Paoli Calmettes
Oncology
Marseille, France

Sponsor: Daiichi Sankyo Inc.
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.