Spinal Muscular Atrophy: Nusinersen via ThecaFlex DRx System

We are studying how the body processes nusinersen when given through the ThecaFlex DRx system in adults and children with spinal muscular atrophy. This research aims to compare it to the standard delivery method.

1-2 years Safety phase (I)No Placebo Standard Medicines InjectionHematologyInternal MedicineNeurology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Nusvelta

Spinraza

Spinraza is a medicine used to treat spinal muscular atrophy that helps improve muscle strength and movement.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Drospirenone

Drospirenone is a synthetic progestin used in hormonal birth control to prevent pregnancy and manage menstrual-related symptoms.

Lactose

Lactose is a sugar commonly used as a filler and binder in tablets and capsules.

Nusinersen

Nusinersen is a substance that helps increase a key protein to improve muscle strength and movement in people with spinal muscular atrophy.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Droslind

Drospirenone

Lyzbet

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Regional De Marseille

Pédiatrie

Marseille, France

Assistance Publique Hopitaux De Paris

Pédiatrie

Vaucresson, France

Universitaetsklinikum Essen AöR

Klinik fuer Neurologie

Essen, Germany

Sponsor: Biogen Idec Research Limited

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.