Squamous Cell Carcinoma of the Penis: Lymphadenectomy and Chemotherapy Study

We are studying a treatment combining surgery and chemotherapy for patients with inguinal lymph node metastases. The goal is to see if this approach improves survival and reduces the chance of cancer returning.

>2 years Efficacy phase (II)No Placebo Standard Medicines Oral InjectionOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Aprepitant Aprepitant

Aprepitant is a medicine used to prevent nausea and vomiting caused by chemotherapy or surgery.

Mesna Eg

Mesna Eg is a medicine used to protect the bladder from damage caused by certain chemotherapy drugs.

Paclitaxel

Paclitaxel is a chemotherapy medicine used to treat various types of cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Aprepitant

Aprepitant is a substance that prevents nausea and vomiting by blocking a brain receptor, often used with chemotherapy or after surgery.

Cisplatin

Cisplatin is a substance used in chemotherapy to kill or stop the growth of cancer cells.

Dexchlorpheniramine Maleate

Dexchlorpheniramine maleate is a substance that relieves allergy symptoms such as sneezing, runny nose, and itching.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abutrax

Aova

Apexelsin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Institut De Cancerologie De L Ouest

Oncologie

Angers, France

CHU Gabriel-Montpied

Oncologie

Beaumont, France

Centre Hospitalier Universitaire De Bordeaux

Oncologie

Bordeaux, France

Sponsor: Unicancer

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.