Stem Cell Transplant for Children with Acute Lymphoblastic Leukemia

We are studying different conditioning treatments for children and adolescents with acute lymphoblastic leukemia undergoing stem cell transplantation. Our goal is to find out which treatment leads to better survival and fewer side effects.

1-2 years≤5 visitsEfficacy phase (II)Confirmation phase (III)No PlaceboInvestigational MedicinesInjectionHematologyOncologyPediatrics

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Blincyto
Blincyto is a cancer medicine used to treat certain types of acute lymphoblastic leukemia by helping the immune system target leukemia cells.
Etoposide
Etoposide is a chemotherapy medicine used to treat various types of cancer.
Thiotepa
Thiotepa is a chemotherapy medicine used to treat certain cancers and sometimes given before bone marrow transplant.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Anti-T Lymphocyte Immunoglobulin For Human Use
Anti-T lymphocyte immunoglobulin is a preparation of antibodies that reduces activity of immune T cells to prevent or treat organ transplant rejection.
Blinatumomab
Blinatumomab is a substance that directs the immune system to attack certain leukemia cells, used for treating some types of acute lymphoblastic leukemia.
Busulfan
Busulfan is a substance used to destroy bone marrow cells before a bone marrow transplant and to treat certain blood cancers.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Rabbit Anti-Human Thymocyte Immunoglobulin

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Celltop
Ebeposid
Eposin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medical University Of Graz
Pädiatrische Hämato-Onkologie
Graz, Austria
Medizinische Universitaet Innsbruck
Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation
Innsbruck, Austria
St. Anna Kinderspital GmbH
Hämatologische, Onkologische und Immunologische Abteilung, Stammzelltransplantationseinheit
Vienna, Austria
Sponsor: St. Anna Childrens Cancer Research Institute GmbH
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.