Systemic Lupus Erythematosus: CABA-201 T Cell Therapy

We are studying a new T cell therapy for people with active systemic lupus erythematosus to see if it is safe and effective. This research aims to understand how it affects disease activity and overall health.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cabazitaxel Cf
Cabazitaxel Cf is a chemotherapy medicine used to treat advanced prostate cancer that has stopped responding to other treatments.
Cyclophosphamide Sandoz
Cyclophosphamide Sandoz is a chemotherapy medicine used to treat various cancers and some severe autoimmune conditions by suppressing the immune system.
Fludarabina Teva
Fludarabina Teva is a chemotherapy medicine used to treat certain blood cancers.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cabazitaxel
Cabazitaxel is a chemotherapy substance used to treat advanced prostate cancer by killing rapidly dividing cells.
Cyclophosphamide
Cyclophosphamide is a cancer-fighting and immune-suppressing substance used to treat various cancers and some severe autoimmune conditions.
Cyclophosphamide Monohydrate
Cyclophosphamide monohydrate is an anti-cancer substance used to treat various cancers and some serious autoimmune diseases.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Bendarabin
Bendarabin
Beneflur

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Poitiers
Service de néphrologie et transplantation rénale
Saint-Benoît, France
Clinica Universidad De Navarra
Unidad de Ensayos Clínicos
Ciudad Lineal, Spain
Clinica Universidad De Navarra
Unidad de Ensayos Clínicos
Pamplona, Spain
Sponsor: Cabaletta Bio Inc.
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.