TAILORED-PROM: Personalized Treatment for Preterm Premature Rupture of Membranes

We are studying if a customized antibiotic and steroid therapy can help prolong pregnancy and improve outcomes for mothers and newborns. This approach may reduce unnecessary antibiotic use compared to standard treatments.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Ampicillin
Ampicillin is an antibiotic substance used to treat various bacterial infections.
Ampicillin Sodium
Ampicillin sodium is an antibiotic substance used to treat a range of bacterial infections.
Benzathine Benzylpenicillin
Benzathine benzylpenicillin is an antibiotic used to treat and prevent certain bacterial infections, including syphilis and rheumatic fever.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Fakultni Nemocnice Brno
Gynekologicko-porodnicka klinika
Brno, Czechia
The Institute For The Care Of Mother And Child
Department of Obstetrics and Gynecology
Prague, Czechia
Vseobecna Fakultni Nemocnice V Praze
Klinika Gynekologie Porodnictvi a Neonatologie
Prague, Czechia
Sponsor: Vseobecna Fakultni Nemocnice V Praze
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.