TAK-330 for Reversing Blood Thinner Effects in Urgent Surgery

We are studying whether TAK-330 can effectively reverse the effects of certain blood thinners in patients needing urgent surgery. This trial compares TAK-330 to the standard treatment to see which works better.

≤3 months ≤5 visits Confirmation phase (III)Post-Trial Drug Access No Placebo Cost Reimbursement Partially Remote Standard Medicines InjectionHematologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Prothromplex Total

Prothromplex Total is a medicine used to quickly stop or prevent serious bleeding by replacing missing blood clotting factors and reversing blood thinners.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Human Coagulation Factor Ii

Human Coagulation Factor II is a protein that helps blood clot and can replace missing clotting factor in people with bleeding disorders.

Human Coagulation Factor Ix

Human coagulation Factor IX is a protein that helps blood clot and is used to prevent and control bleeding in people with hemophilia B.

Human Coagulation Factor Vii

Human Coagulation Factor VII is a substance that helps blood clot to control bleeding in people with certain clotting disorders.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alphanate

Beriate

Beriate 1000

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medical University Of Graz

Clinical Department of Anesthesiology and Intensive Medicine 1

Graz, Austria

Noe LGA Gesundheit Thermenregion GmbH

Department of Anesthesia and Intensive Care Medicine

Neunkirchen, Austria

A.O. Krankenhaus St. Josef Braunau GmbH

Internal Medicine 1

Simbach am Inn, Austria

Sponsor: Takeda Development Center Americas Inc.

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.