Talquetamab: Reducing Oral Side Effects

We are testing ways to lessen taste changes caused by talquetamab in patients undergoing treatment. The goal is to find effective methods to improve the experience for those affected.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Clonazepam
Clonazepam is a medication used to prevent seizures and to treat panic attacks.
Pregabalin Ratiopharm
Pregabalin Ratiopharm is a medicine used to relieve nerve-related pain and to help control seizures and some anxiety disorders.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Clonazepam
Clonazepam is a substance that helps prevent seizures and reduces severe anxiety or panic attacks.
Dexamethasone
Dexamethasone is a steroid that reduces inflammation and suppresses the immune system to treat allergic, inflammatory, and autoimmune conditions.
Pregabalin
Pregabalin is a substance that eases nerve-related pain and is used to treat certain seizures and anxiety.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Jnj-64407564

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aciryl
Aclaton
Aklonil

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Amsterdam UMC Stichting
Hematology
Amstelveen, Netherlands
Albert Schweitzer Ziekenhuis
Hematology
Dordrecht, Netherlands
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Hematology
Rotterdam, Netherlands

Sponsor: Janssen - Cilag International
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.