Non-Hodgkin Lymphoma
Non-Hodgkin Lymphoma (NHL) is a type of cancer that originates in the lymphatic system, which is part of the immune system. It can cause symptoms like swollen lymph nodes, fever, night sweats, and unexplained weight loss.
Targeted Anti-Cancer Drugs: DRUP Trial
We are studying how well existing targeted drugs work for patients with advanced cancers that have specific genetic markers. This trial aims to improve access to effective treatments and gather important data on their use.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Advanced Solid Tumor
An advanced solid tumor refers to a mass of cancer cells that has grown beyond its original site and may have spread to other parts of the body. Symptoms can vary widely depending on the tumor's location but may include pain, weight loss, and fatigue.
T-cell Prolymphocytic Leukemia
T-cell Prolymphocytic Leukemia (T-PLL) is a rare and aggressive form of leukemia that affects T-cells, a type of white blood cell. Symptoms may include fatigue, swollen lymph nodes, and frequent infections.
Multiple Myeloma
Multiple Myeloma (MM) is a cancer of the plasma cells in the bone marrow, leading to the production of abnormal proteins. Symptoms can include bone pain, fatigue, and increased susceptibility to infections.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you over 18 years old?
- Do you have a solid tumor, multiple myeloma, or non-Hodgkin lymphoma that has progressed after treatment?
- Are you currently pregnant or breastfeeding?
- Are you taking any anti-cancer therapy, including chemotherapy or radiation, right now?
- Do you have any serious heart problems, like uncontrolled angina or heart failure?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Perjeta
Mekinist
Rubraca
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Abevmy
Aksitinib Alpha-Medical
Aksitinib Sandoz
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Academisch Medisch Centrum
Oncology
Abcoude, Netherlands
Noordwest Ziekenhuisgroep Stichting
Medical Oncology
Alkmaar, Netherlands
Ziekenhuisgroep Twente Stichting
Internal Medicine and Gastrointestinal liver disease
Almelo, Netherlands
Sponsor: Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.