Tezepelumab for Progressive Pulmonary Fibrosis

We are studying whether Tezepelumab can help reduce symptoms and improve lung function in people with progressive pulmonary fibrosis and high eosinophil levels. This trial compares the medication to a placebo to evaluate its effectiveness.

1-2 years 6-10 visits Efficacy phase (II)Post-Trial Drug Access Partially Remote Standard Medicines InjectionPulmonology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Tezspire

Tezspire is a medicine used to treat severe asthma by reducing attacks and helping improve breathing.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Methylcellulose

Methylcellulose is a substance that softens and increases stool bulk to relieve constipation.

Tezepelumab

Tezepelumab is a substance that blocks an immune protein to reduce severe asthma attacks and improve breathing for people with uncontrolled asthma.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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LungenClinic Grosshansdorf GmbH

Pneumologie

Großhansdorf, Germany

Ruhrlandklinik Westdeutsches Lungenzentrum Am Universitaetsklinikum Essen gGmbH

Klinik für Pneumologie

Heiligenhaus, Germany

Medizinische Hochschule Hannover

Klinik für Pneumologie und Infektiologie

Laatzen, Germany

Sponsor: Philipps-Universitaet Marburg

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.