Thyroid Eye Disease
Thyroid Eye Disease (TED) is an autoimmune condition that affects the eyes, often causing symptoms like bulging eyes, discomfort, and vision changes due to inflammation of the eye muscles and surrounding tissues.
Thyroid Eye Disease: Lu AG22515 Treatment
We are investigating the effects of Lu AG22515 on eye bulging in adults with moderate-to-severe Thyroid Eye Disease. This study aims to see if it can improve symptoms related to this condition.
1-2 years16-20 visitsSafety phase (I)No PlaceboCost ReimbursementInvestigational MedicinesInjectionEndocrinologyOphthalmology
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 18 and 75 years old?
- Do you have Graves’ disease with symptoms of Thyroid Eye Disease (TED)?
- Have you had any serious eye problems, like vision loss or eye surgery, in the last 6 months?
- Are you currently taking any systemic corticosteroids like Prednisone or Dexamethasone?
- Have you had any serious infections that required hospitalization in the last 8 weeks?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Human (scfv)2-Fab Fusion Protein Against Cd40l
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Diagnostic-Consultative Center Alexandrovska EOOD
Ophthalmology Department at Medical University of Sofia
Sofia, Bulgaria
University Specialized Hospital For Active Treatment In Endocrinology (USHATE) "Acad. Ivan Penchev"
Third Clinic - Endocrinology and Metabolic Diseases
Sofia, Bulgaria
Universitaetsklinikum Tuebingen AöR
Research Institute for Ophthalmology / Forschungsinstitut für Augenheilkunde
Tübingen, Germany
Sponsor: H. Lundbeck A/S
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.