Thyroid Eye Disease
Thyroid eye disease is an autoimmune condition that affects the eyes, often causing symptoms like bulging eyes, swelling, and discomfort. It is commonly associated with thyroid disorders, particularly hyperthyroidism.
Thyroid Eye Disease: TOUR006 Treatment Study
We are investigating whether the new treatment TOUR006 can reduce eye bulging in adults with thyroid eye disease. Participants will receive either the treatment or a placebo to compare effects.
1-2 years≤5 visitsEfficacy phase (II)Cost ReimbursementInvestigational MedicinesInjectionEndocrinologyOphthalmology
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you diagnosed with Graves' disease with moderate to severe active thyroid eye disease (TED)?
- Have you had symptoms of active TED in the last 15 months?
- Do you have noticeable bulging of the eyes (proptosis) that is more than 3 mm above normal?
- Are you currently pregnant or breastfeeding?
- Have you taken steroids like Prednisone or Dexamethasone in the last 6 weeks?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Human IgG2 Monoclonal Antibody Against IL-6
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Centre Hospitalier Universitaire D'Angers
Endocrinologie, Diabétologie et Nutrition
Angers, France
Centre Hospitalier Universitaire De Nantes
Endocrinologie, Diabétologie et Nutrition
Orvault, France
Azienda Ospedaliero Universitaria Pisana
Endocrinologist
Pisa, Italy
Sponsor: Tourmaline Bio Inc.
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.