Thyroid Eye Disease
Thyroid Eye Disease (TED) is an autoimmune condition that affects the eyes, often associated with hyperthyroidism, leading to symptoms such as bulging eyes, swelling, and discomfort.
Thyroid Eye Disease: VRDN-001 Treatment Study
We are testing the safety and tolerability of a new monoclonal antibody, VRDN-001, in people with thyroid eye disease. This study involves receiving intravenous infusions to see how well the treatment is tolerated.
1-2 years≤5 visitsConfirmation phase (III)No PlaceboInvestigational MedicinesInjectionEndocrinologyOphthalmology
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 18 and 75 years old?
- Are you currently pregnant or breastfeeding?
- Have you used systemic corticosteroids in the last 2 weeks?
- Have you received any treatment for TED in the last 8 weeks?
- Have you ever been treated with another anti-IGF-1R therapy?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Vrdn-001
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Centre Hospitalier Regional D'Angers
1502:Service Endocrinologie, Diabetologie et Nutrition
Angers, France
Centre Hospitalier Universitaire De Nice
1505:Ophtalmologie
Nice, France
Quinze-Vingts National Ophthalmology Hospital
1509:Medecine Interne
Quinze-Vingts, France
Sponsor: Viridian Therapeutics S.à.r.l.
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.