Depression
Depression is a medical condition that affects how you feel, think, and act, often causing persistent sadness or loss of interest in activities you once enjoyed.
Treatment-Resistant Depression: P-glycoprotein Study
We are investigating how a protein may affect people with treatment-resistant depression using advanced imaging. This study compares P-glycoprotein activity in those who do not respond to treatment with those who do.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 18 and 65 years old?
- Do you have a diagnosis of major depressive disorder (MDD)?
- Are you currently taking any medications that affect P-glycoprotein activity, like certain antidepressants?
- Have you had any drug or alcohol abuse or dependence in the last 6 years?
- Are you pregnant, breastfeeding, or planning to become pregnant in the next 6 months?
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
U.O.C. di Psichiatria Clinica e d’Urgenza
La Massimina-Casal Lumbroso, Italy
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.