Triple-Negative Early Breast Cancer: Sacituzumab Govitecan with or without Pembrolizumab

We are comparing two treatment options for low-risk, triple-negative early breast cancer to see which is more effective. The study also evaluates how these treatments affect patients' quality of life.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Keytruda
Keytruda is a cancer medicine that helps the immune system find and fight tumor cells.
Trodelvy
Trodelvy is a cancer medicine used to treat certain advanced or metastatic breast and bladder cancers.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Pembrolizumab
Pembrolizumab is a substance that helps the immune system recognize and attack certain cancers by blocking a protein called PD-1.
Sacituzumab Govitecan
Sacituzumab govitecan is an antibody-based cancer treatment that targets tumor cells and delivers a cell-killing agent to shrink certain advanced cancers.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Haematologie-Onkologie im Zentrum MVZ GmbH
Hämatologie-Onkologie im Zentrum MVZ GmbH
Augsburg, Germany
Klinikum Mittelbaden Balg
Brustzentrum Baden-Baden Balg
Baden-Baden, Germany
Charite Universitaetsmedizin Berlin KöR
Frauenklinik - Brustzentrum
Berlin, Germany

Sponsor: WSG Westdeutsche Studiengruppe GmbH
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.