Ulcerative Colitis: Eltrekibart Treatment Study

We are studying whether eltrekibart can help adults with moderately to severely active ulcerative colitis achieve remission. This trial compares the effects of eltrekibart to a placebo.

1-2 years16-20 visitsEfficacy phase (II)Post-Trial Drug AccessCost ReimbursementPartially RemoteInvestigational MedicinesInjectionGastroenterologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Clexane
Clexane is a medicine that helps prevent and treat harmful blood clots.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Enoxaparin Sodium
Enoxaparin sodium is a substance that helps prevent and treat blood clots by thinning the blood.
Mirikizumab
Mirikizumab is a lab-made antibody that reduces immune-driven inflammation to treat conditions such as ulcerative colitis and plaque psoriasis.
Sodium Chloride Solution 0.9%
Sodium chloride 0.9% is a sterile salt solution used to replace fluids and electrolytes, hydrate patients, and clean wounds or body cavities.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Eltrekibart
Cxcl1
Cxcl2

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Arovi
Clexane 6 000 Ui
Clexane Forte

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre hospitalier universitaire de Tivoli Institut medical des Mutualites socialistes
Gastro-enterelogy
Haine-Saint-Pierre, Belgium
Centre Hospitalier Universitaire Dinant Godinne Sainte-Elisabeth-UCL-Namur
Gastro-enterelogy
Profondeville, Belgium
Opca Bolnica Dr. Andelko Visic Bjelovar
Gastroenterology and Pulmology
Bjelovar, Croatia
Sponsor: Eli Lilly & Co.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.