Ulcerative Colitis: Lutikizumab Treatment Study

We are assessing the safety and effectiveness of lutikizumab in adults with active ulcerative colitis. This study compares it to an existing treatment to see if it offers better results.

1-2 years >20 visits Efficacy phase (II)Post-Trial Drug Access Cost Reimbursement Partially Remote Investigational Medicines Oral InjectionGastroenterologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Humira

Humira is a medicine that reduces inflammation by calming the immune system to treat autoimmune conditions such as arthritis and Crohn’s disease.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Adalimumab

Adalimumab is a biologic that blocks a key inflammatory protein (TNF) to reduce inflammation in autoimmune conditions like rheumatoid arthritis and Crohn's disease.

Infliximab

Infliximab is a substance that reduces inflammation by blocking a protein called TNF and is used for autoimmune conditions like rheumatoid arthritis and Crohn's.

Placebo

Placebo is an inactive substance given to mimic a treatment so researchers can measure effects caused by patients' expectations.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Lutikizumab

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Amgevita

Amsparity

Hefiya

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Gemeinnutzige Salzburger Landes kliniken Betriebsgesellschaft mbH

LKH Salzburg, Department of Internal Medicine I

Salzburg, Austria

Noe LGA Gesundheit Region Mitte GmbH

University Hospital St. Poelten, Department of Internal Medicine II

Sankt Pölten, Austria

Medical University Of Vienna

Department of Internal Medicine III, Division of Gastroenterology and Hepatology

Vienna, Austria

Sponsor: AbbVie Deutschland GmbH & Co. KG

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.