Uterine Leiomyosarcoma: Post-Operative Chemotherapy Study

We are investigating whether adding chemotherapy after surgery helps patients with high-risk localized uterine leiomyosarcoma avoid relapse. This study compares the new treatment approach to standard observation care.

≤5 visits Efficacy phase (II)No Placebo Standard Medicines InjectionGynecology and ObstetricsOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Doxorubicine Arrow

Doxorubicine Arrow is a chemotherapy medicine used to treat various types of cancer.

Yondelis

Yondelis is a cancer medicine used to treat certain soft tissue sarcomas and some cases of ovarian cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Doxorubicin Hydrochloride

Doxorubicin hydrochloride is a chemotherapy substance used to treat various cancers by killing or slowing the growth of cancer cells.

Trabectedin

Trabectedin is a substance used to treat certain types of cancer, especially some soft tissue sarcomas and ovarian cancer.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adriacept Blasen-Instillations-Set

Adriamycin

Adriblastin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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INSTITUT DE CANCEROLOGIE DE L’OUEST (ICO), SITE P PAPIN

Oncologie

Angers, France

Assistance Publique Hopitaux De Paris

Oncologie

Bagnolet, France

Groupe Hospitalier Diaconesses Croix Saint Simon

Oncologie

Bagnolet, France

Sponsor: Unicancer

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.