Uveal Melanoma: New Liver Treatment with Ipilimumab and Nivolumab

We are testing a new liver treatment combined with two immunotherapy drugs for patients with uveal melanoma that has spread to the liver. This study aims to see if the new approach improves survival without disease progression compared to standard treatment.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Opdivo
Opdivo is a cancer medicine that helps the immune system find and fight tumor cells.
Yervoy
Yervoy is a cancer medicine that helps the immune system find and attack melanoma and some other types of tumors.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Ipilimumab
Ipilimumab is a substance that helps the immune system attack cancer by blocking a protein that keeps immune cells from working.
Nivolumab
Nivolumab is a substance that helps the immune system recognize and attack certain cancers.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Alkeran

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Opdualag

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Sahlgrenska University Hospital-Vastra Gotalandsregionen
Sahlgrenska University Hospital Dept. of Oncology Blå stråket 2 SE-413 45 Gothenburg, Sweden
Göteborg, Sweden
Linkoping University Hospital Region Ostergotland
Linköping University Hospital, Linköping, Sweden
Linköping, Sweden
Region Skane Skanes Universitetssjukhus
Skåne University Hospital Dept. of Oncology 222 42 Lund, Sweden
Lund, Sweden

Sponsor: Vaestra Goetalandsregionen
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.