Vedolizumab for Children with Moderate to Severe Crohn's Disease

We are studying how well different doses of vedolizumab help children and teenagers with Crohn's disease maintain their health. The goal is to see if it can keep symptoms under control and improve their overall well-being.

1-2 years Confirmation phase (III)Post-Trial Drug Access No Placebo Cost Reimbursement Standard Medicines Oral InjectionGastroenterologyPediatrics

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Budesonide

Budesonide is a medicine that reduces swelling in the lungs and airways to help people with asthma and other breathing problems.

Entyvio

Entyvio is a medicine used to treat moderate to severe ulcerative colitis and Crohn’s disease by reducing inflammation in the gut.

Prednisone Eg

Prednisone Eg is a steroid medicine that reduces inflammation and treats allergic, autoimmune, and other inflammatory conditions.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Budesonide

Budesonide is a steroid substance that reduces inflammation in the airways to help control asthma and other respiratory conditions.

Ibuprofen

Ibuprofen is a substance that reduces pain, fever, and inflammation.

Prednisone

Prednisone is a steroid substance that reduces inflammation and suppresses the immune system for conditions like allergies, asthma, and autoimmune disorders.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

200 Mg + 500 Mg

3 Months Ibuprofen Strawberry Flavour

3 Months Plus Strawberry Flavour

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Brussel

Pediatric Gastoenterology

Ganshoren, Belgium

UZ Leuven

Pediatric Gastoenterology

Heverlee, Belgium

Antwerp University Hospital

Pediatric Gastoenterology

Wilrijk, Belgium

Sponsor: Takeda Development Center Americas Inc.

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.