Vericiguat for Vasospastic Angina

We are studying how vericiguat affects heart function and angina episodes in patients with vasospastic angina. The trial also looks at quality of life and safety of the treatment.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Miochol-E
Miochol-E is an eye medicine used during eye surgery to make the pupil smaller and help the surgeon position the artificial lens.
Miovisin
Nitroprussid-Natrium Aftpharm
Nitroprussid-Natrium Aftpharm is a hospital medicine used to quickly lower very high blood pressure in emergency situations.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Acetylcholine Chloride
Acetylcholine chloride is a substance that mimics the body's neurotransmitter to stimulate muscles and rest-and-digest responses, used in research and some eye procedures.
Insulin Aspart
Insulin aspart is a fast-acting insulin used to quickly lower blood sugar in people with diabetes.
Sodium Nitroprusside
Sodium nitroprusside is a substance that quickly lowers dangerously high blood pressure by relaxing blood vessels.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Fiasp
Fiasp Flextouch
Fiasp Penfill

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Amsterdam UMC
Cardiology
Abcoude, Netherlands
Sponsor: Amsterdam UMC
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.