Acute Respiratory Failure
Acute respiratory failure is a life-threatening condition where the lungs cannot provide enough oxygen to the body or remove carbon dioxide, often resulting from severe lung infections or other respiratory issues.
Viral Lung Infection: Tozorakimab Study
We are testing the new medication tozorakimab in patients hospitalized for viral lung infections requiring oxygen. The goal is to see if it can help prevent serious complications compared to a placebo.
≤3 months≤5 visitsConfirmation phase (III)Cost ReimbursementPartially RemoteInvestigational MedicinesInjectionInternal MedicinePulmonology
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Severe Viral Lung Infections
Severe viral lung infections can lead to significant respiratory distress and may result in acute respiratory failure, causing symptoms like cough, fever, and difficulty breathing.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you 18 years old or older?
- Have you been hospitalized with a viral lung infection?
- Do you need supplemental oxygen because your oxygen levels are low?
- Are you currently on mechanical ventilation or ECMO (a type of life support)?
- Do you have any solid tumors that have spread (Stage IV cancer) or blood cancers like lymphoma or leukemia that are not in complete remission?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Tozorakimab
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Algemeen Ziekenhuis Groeninge
Longziekten
Kortrijk, Belgium
Clinique Saint-Pierre
Soins Intensifs
Ottignies, Belgium
Algemeen Ziekenhuis Delta
Longziekten
Rumbeke, Belgium
Sponsor: Astrazeneca AB
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.