Vitiligo Treatment: Methotrexate and UVB Phototherapy

We are studying whether combining methotrexate with UVB phototherapy helps adults with progressive vitiligo achieve better skin repigmentation. We will also assess the safety of this treatment and its impact on quality of life.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Calcium Folinate
Calcium folinate is a form of folate used to treat folate deficiency and reduce harmful effects of some chemotherapy.
Folic Acid
Folic acid is a B vitamin that helps make healthy red blood cells and prevent birth defects when taken during pregnancy.
Methotrexate
Methotrexate is a substance that slows rapid cell growth and calms the immune system to treat certain cancers and autoimmune conditions.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Microcrystalline Cellulose

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Bordeaux
Dermatologie de l’Adulte et de l’Enfant
Bordeaux, France
Centre Hospitalier De Pau
Dermatologie
Pau, France
Centre Hospitalier De Perigueux
Dermatologie
Périgueux, France

Sponsor: Centre Hospitalier Universitaire De Bordeaux
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.