ZN-c3 for High-Grade Serous Ovarian Cancer

We are studying a new treatment called azenosertib for individuals with high-grade serous ovarian cancer. The trial aims to evaluate its safety and effectiveness, especially in patients with a specific genetic marker.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Akynzeo
Akynzeo is a medicine used to prevent nausea and vomiting caused by chemotherapy.
Aprepitant Aprepitant
Aprepitant is a medicine used to prevent nausea and vomiting caused by chemotherapy or surgery.
Granisetron Actavis
Granisetron Actavis is a medicine that helps prevent nausea and vomiting from chemotherapy, radiation, or surgery.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Aprepitant
Aprepitant is a substance that prevents nausea and vomiting by blocking a brain receptor, often used with chemotherapy or after surgery.
Betamethasone Sodium Phosphate Ph. Eur
Betamethasone sodium phosphate is a substance that reduces inflammation and calms the immune system.
Dexamethasone
Dexamethasone is a steroid that reduces inflammation and suppresses the immune system to treat allergic, inflammatory, and autoimmune conditions.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Azenosertib

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aloxi
Aloxi
Aprepilor

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Onze-Lieve-Vrouwziekenhuis
Medical Oncology
Aalst, Belgium
UZ Leuven
Gynecologic Oncology
Heverlee, Belgium
Centre Hospitalier Universitaire Dinant Godinne Sainte-Elisabeth-UCL-Namur
Oncology
Saint-Servais, Belgium

Sponsor: K-Group Beta Inc.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.