Search Clinical Trials in the European Union

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3881-3900 of 3,900 trials

Kidney Protection: Semaglutide and Finerenone in CKD

We are studying how semaglutide and finerenone may help protect the kidneys in people with chronic kidney disease. This includes patients with and without diabetes to explore their effects and mechanisms.

Chronic Kidney Disease6-12 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteEndocrinologyNephrology

Rheumatoid Arthritis: Methotrexate and Novobiocin Study

We are investigating how a combination of Methotrexate and Novobiocin affects patients with rheumatoid arthritis. This study aims to learn more about the treatment's effectiveness and safety.

Rheumatoid Arthritis6-12 monthsSafety phase (I)Rheumatology

Comparing PB016 to Entyvio for Healthy Participants

We are studying a new treatment to see how it works and its safety compared to an established medication. This trial involves healthy individuals to help us understand the differences between the two.

Healthy Participants6-12 monthsSafety phase (I)GastroenterologyInternal Medicine

O3R-5671-PRO: Tolerance Study in Healthy Adults

We are evaluating how well healthy adults tolerate single and multiple doses of the new medication O3R-5671-PRO. This study aims to ensure the safety of the drug for future use.

Inflammatory Bowel DiseasePsoriasis3-6 monthsSafety phase (I)DermatologyInfectious DiseasesInternal Medicine

Prazosin Absorption Study in Healthy Adults

We are investigating how different forms of Prazosin are absorbed into the blood in healthy adults. This research may help improve how this medication is used in future treatments.

High Blood Pressure and Heart Failure6-12 monthsSafety phase (I)CardiologyInternal Medicine

Influenza Vaccine Study: Seqirus H5N8

We are investigating how well the Seqirus H5N8 influenza vaccine works in adults who have been previously vaccinated and those who have never received an H5 vaccine. The study aims to assess immune responses and safety in both groups.

H5N1 Influenza Immunization≤3 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesInfectious Diseases

Influenza Vaccine Study for Adults

We are assessing a new mRNA-based vaccine to see how well it boosts the immune response and its safety in adults aged 18 and older. This study aims to improve protection against seasonal influenza.

Human Influenza6-12 monthsEfficacy phase (II)≤5 visitsPost-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementInfectious Diseases

Metastatic Breast Cancer: Trastuzumab-Deruxtecan Study

We are studying how body weight influences the effects and side effects of trastuzumab-deruxtecan in patients with metastatic breast cancer. This research may help improve treatment strategies for different body types.

Metastatic Breast Cancer>2 yearsMonitoring phase (IV)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesPartially RemoteInternal MedicineOncology

CTNNB1 Syndrome: Gene Therapy Study for Kids

We are testing a new gene therapy given through an injection in the brain for children with CTNNB1 syndrome. The study aims to see if it is safe and if it may help improve their condition.

CTNNB1 Syndrome1-2 yearsSafety phase (I)Efficacy phase (II)>20 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteNeurologyPediatrics

Advanced Solid Tumors: NDI-219216 Treatment

We are testing a new drug called NDI-219216 in patients with advanced solid tumors, including those with specific genetic markers. The goal is to understand its safety and how it may work in these patients.

Advanced Solid Tumors>2 yearsSafety phase (I)Oncology

Vonafexor Acid: Comparing Two Forms

We are examining how two versions of Vonafexor Acid work in the body and if they interact with other medications. This study is for individuals interested in understanding new treatment options.

Healthy Volunteers with Impaired Renal Function and Suspected MASHSafety phase (I)EndocrinologyGastroenterology

MSP-2020: Effects on Brain Activity in Healthy Adults

We are examining how MSP-2020 affects brain activity in healthy adults. This study aims to understand its potential impact on cognitive functions.

Major Depressive Disorder6-12 monthsSafety phase (I)Psychiatry

Type 1 Diabetes: GZR33 Insulin Study

We are evaluating a new insulin called GZR33 to see how it compares to insulin Degludec in managing Type 1 Diabetes. The study focuses on its effectiveness, safety, and how the body processes it.

Type 1 Diabetes3-6 monthsSafety phase (I)DiabetologyEndocrinology

Safety Study of AX-5006 in Parkinson's Disease

We are investigating the safety of a new treatment called AX-5006 for people with and without Parkinson's disease. This research aims to understand how the agent affects different individuals.

Parkinson's Disease6-12 monthsSafety phase (I)Neurology

ARV-102: Food and Esomeprazole Interaction Study

We are investigating how food and a common heartburn medication affect the way a new drug is absorbed in healthy individuals. This research may help improve future treatments.

Parkinson's Disease6-12 monthsSafety phase (I)Neurology

2-Methoxyestradiol: Dose Study in Healthy Women

We are investigating how different doses of 2-Methoxyestradiol affect healthy non-pregnant women. This research may help us understand its potential uses in future treatments.

Healthy Participants6-12 monthsSafety phase (I)Gynecology and Obstetrics

MK-6050: Study in Healthy Volunteers

We are investigating the effects of MK-6050 in healthy individuals. This research aims to gather important safety information about the medication.

Hidradenitis Suppurativa3-6 monthsSafety phase (I)AllergologyDermatology

Safety Study of NRG5051 in Parkinson's Disease and ALS

We are investigating the safety of a new treatment called NRG5051 in healthy adults and patients with Parkinson's disease or ALS. This research aims to understand how the drug affects different groups of people.

Parkinson's Disease and Amyotrophic Lateral Sclerosis (ALS)Safety phase (I)Neurology

Nicotine Pouch vs. Nicorette® Lozenge in Smokers

We are comparing how a new 4 mg nicotine pouch works in the body compared to a 4 mg Nicorette® lozenge. This study is for healthy adults who currently use cigarettes.

Nicotine UseSafety phase (I)Psychiatry

COVID-19 Vaccine Study: BIMERVAX® LP.8.1

We are evaluating the safety and immune response of the BIMERVAX® LP.8.1 vaccine against COVID-19 variants. This study aims to understand how well it works in generating antibodies to fight the virus.

COVID-19≤3 monthsMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesInfectious Diseases