Search Clinical Trials in the European Union

1-2 years
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141-160 of 653 trials

Hidradenitis Suppurativa: New Antibiotic Treatment Study

We are evaluating a new antibiotic regimen for people with Hurley stage 2 Hidradenitis Suppurativa to see if it works better than standard treatment. The study will also look at pain relief and quality of life improvements.

Hidradenitis Suppurativa1-2 yearsConfirmation phase (III)6-10 visitsInvestigational MedicinesDermatologyInfectious Diseases

HIV Treatment: Doravirine/Tenofovir/Lamivudine Study

We are studying a combination of medications for people living with HIV who have a history of specific mutations. The goal is to see if this treatment helps maintain viral control and improves health over time.

HIV Disease1-2 yearsEfficacy phase (II)No PlaceboStandard MedicinesInfectious DiseasesInternal Medicine

Metastatic Castration-Resistant Prostate Cancer: Gedatolisib and Darolutamide Study

We are studying a new combination of gedatolisib and darolutamide for men with metastatic castration-resistant prostate cancer. The trial will evaluate safety, tolerability, and how well this treatment works.

Castration-Resistant Prostate Cancer1-2 yearsSafety phase (I)Efficacy phase (II)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesPartially RemoteOncologyUrology

Sinonasal Carcinoma: Pembrolizumab and Chemotherapy

We are studying the safety and effectiveness of combining pembrolizumab with chemotherapy for patients with locally advanced sinonasal carcinoma. This trial aims to explore new treatment options for better outcomes.

Locally Advanced Sinonasal Carcinoma1-2 yearsEfficacy phase (II)≤5 visitsNo PlaceboStandard MedicinesOncologyOtolaryngology

Allergy Relief: Sublingual Immunotherapy for House Dust Mite Allergies

We are studying a new treatment for individuals aged 12-65 with rhinitis or asthma caused by house dust mites. The goal is to see if this therapy can improve allergy symptoms compared to a placebo.

Allergic Rhinitis and Asthma1-2 yearsConfirmation phase (III)Investigational MedicinesAllergologyPulmonology

Ovarian Cancer: 68Ga-FAPI PET/CT Imaging Study

We are comparing a new imaging technique to standard methods for diagnosing and monitoring ovarian cancer. This study aims to see if the new method improves patient management and safety.

Ovarian Cancer1-2 yearsEfficacy phase (II)No PlaceboInvestigational MedicinesOncologyOtolaryngology

Type 2 Diabetes: Semaglutide for Bone Health

We are investigating whether oral Semaglutide can improve bone formation and strength in men and women with type 2 diabetes. This study focuses on those with normal or low bone mass.

Type 2 Diabetes1-2 yearsEfficacy phase (II)6-10 visitsInvestigational MedicinesCost ReimbursementDiabetologyEndocrinologyRheumatology

HMB-001 for Glanzmann Thrombasthenia

We are investigating a new treatment to see if it is safe and can help reduce bleeding in people with Glanzmann Thrombasthenia. This study will also look at how the body processes the medication and its effects on quality of life.

Glanzmann's Disease1-2 yearsSafety phase (I)Efficacy phase (II)11-15 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteHematology

Nebulized Fentanyl: Facial vs. Intranasal Delivery

We are comparing two ways to deliver nebulized fentanyl to healthy volunteers. This study aims to understand which method may be more effective for future use.

Healthy Volunteers1-2 yearsSafety phase (I)Internal MedicineOtolaryngologyPsychiatryPulmonology

Pain Management: Dexmedetomidine for Nerve Block

We are exploring the best dose of dexmedetomidine to enhance pain relief during a nerve block procedure. This study will also check for side effects and benefits like reduced opioid use and better patient satisfaction.

Patients Scheduled for Shoulder Operations1-2 yearsConfirmation phase (III)Monitoring phase (IV)No PlaceboStandard MedicinesInternal MedicineNeurologyOrthopedics and TraumatologyOtolaryngology

Achondroplasia: TransCon CNP Treatment for Infants

We are investigating the safety and growth effects of weekly injections of TransCon CNP in infants with achondroplasia. This study aims to understand how the treatment may help with growth and development.

Achondroplasia1-2 yearsEfficacy phase (II)11-15 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementEndocrinologyPediatrics

Heart Failure: Trimetazidine Study

We are investigating how trimetazidine affects heart function and health markers in people with heart failure. The goal is to see if it can improve symptoms and reduce hospital visits.

Heart Failure with Preserved Ejection Fraction1-2 yearsMonitoring phase (IV)Standard MedicinesCardiologyInternal Medicine

Fluorescence Imaging in Crohn’s Disease and Psoriasis

We are exploring a new imaging technique to help diagnose and monitor Crohn’s disease and psoriasis. This study aims to see if it provides clearer insights into these conditions.

Crohn's DiseasePsoriasis1-2 yearsSafety phase (I)AllergologyDermatologyGastroenterology

Colorectal Liver Metastases: HAIP-SYST Treatment Study

We are investigating a new combination of local and systemic chemotherapy for patients with initially unresectable colorectal liver metastases. The study aims to see if this approach improves survival and quality of life compared to standard treatment.

Colorectal Liver Metastases1-2 yearsConfirmation phase (III)No PlaceboInvestigational MedicinesHepatologyOncology

Obesity in Adolescents: Semaglutide Treatment Study

We are exploring whether a weekly injection of semaglutide can help adolescents with obesity lose weight more effectively than a placebo. This study also looks at the safety and overall health impacts of the treatment.

Obesity1-2 yearsMonitoring phase (IV)6-10 visitsInvestigational MedicinesPartially RemoteEndocrinologyPediatrics

Plaque Psoriasis in Teens: Deucravacitinib Study

We are evaluating a new medication for adolescents with moderate to severe plaque psoriasis to see if it helps improve their skin condition compared to a placebo. The study also looks at safety and how patients feel about their treatment.

Plaque Psoriasis1-2 yearsConfirmation phase (III)11-15 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteAllergologyDermatology

MB-CART2019.1 Therapy for Pediatric B-Cell Neoplasms

We are studying how safe and effective MB-CART2019.1 is for children and teens with relapsed or refractory B-cell cancers. This research aims to find better treatment options for those who haven't responded to other therapies.

Refractory or Recurrent B-cell Lymphoma1-2 yearsEfficacy phase (II)11-15 visitsNo PlaceboInvestigational MedicinesOncologyPediatrics

Healthy Men: Study of Inno8 Dosing

We are researching how different doses of the medicine Inno8 work in the bodies of healthy men. This study may help us understand the best dosing for future treatments.

Haemophilia A1-2 yearsSafety phase (I)AllergologyDermatologyDiabetologyEndocrinologyGynecology and ObstetricsHematologyInfectious DiseasesInternal MedicineNephrologyNeurologyOncologyOphthalmologyOrthopedics and TraumatologyOtolaryngologyPediatricsPsychiatryRheumatologyUrology

Metastatic Lung Cancer: BL-B01D1 Treatment

We are evaluating a new treatment for patients with metastatic or unresectable non-small cell lung cancer and other solid tumors. The study aims to assess its safety and how well it is tolerated.

Non-small Cell Lung Cancer1-2 yearsSafety phase (I)OncologyPulmonology

Mycobacterium abscessus: Optimizing Lung Disease Treatment

We are studying the best treatment options for lung disease caused by Mycobacterium abscessus. Our goal is to see how well these treatments clear the infection and how well patients tolerate them.

Mycobacterium Abscessus Infection1-2 yearsEfficacy phase (II)≤5 visitsNo PlaceboStandard MedicinesPartially RemoteInfectious DiseasesPulmonology