Advanced Clear-Cell Renal Carcinoma: Digital Monitoring with Cabozantinib and Nivolumab

We are studying how digital tracking of symptoms can help adjust treatments for patients with advanced clear-cell renal carcinoma receiving Cabozantinib and Nivolumab. This may improve their overall health and quality of life during treatment.

>2 years 16-20 visits Monitoring phase (IV)No Placebo Partially Remote Standard Medicines Oral InjectionInternal MedicineOncologyUrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cabometyx

Cabometyx is a cancer medicine used to treat certain advanced kidney and liver cancers.

Opdivo

Opdivo is a cancer medicine that helps the immune system find and fight tumor cells.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cabozantinib

Cabozantinib is a substance used to treat certain advanced cancers by blocking signals that help tumors grow and spread.

Nivolumab

Nivolumab is a substance that helps the immune system recognize and attack certain cancers.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Cabozantinib Ipsen

Cometriq

Opdualag

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Annecy Genevois

oncologie médicale

Annecy, France

Institut Sainte Catherine

oncologie médicale

Avignon, France

Centre Hospitalier Aunay Bayeux

oncologie médicale

Bayeux, France

Sponsor: Centre Francois Baclesse

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.