Obesity
Obesity is a medical condition characterized by excessive body fat that increases the risk of health problems, including heart disease and diabetes.
Atrial Fibrillation: Semaglutide for Weight Control
We are studying whether a weekly injection of semaglutide helps people with obesity and atrial fibrillation achieve a normal heart rhythm. The trial also looks at how weight loss affects symptoms and quality of life.
1-2 years≤5 visitsMonitoring phase (IV)Investigational MedicinesInjectionCardiologyEndocrinologyInternal Medicine
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Atrial Fibrillation
Atrial fibrillation (AFib) is a heart condition that causes an irregular and often rapid heartbeat, which can lead to blood clots, stroke, and other heart-related complications.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you at least 18 years old?
- Do you have obesity (BMI of 30 or higher) or a BMI of 27 or higher with a weight-related health issue like high blood pressure or sleep apnea?
- Do you have a history of diabetes (type 1 or type 2)?
- Are you currently pregnant, breastfeeding, or planning to become pregnant?
- Have you had a heart condition called permanent atrial fibrillation?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Semaglutide
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Jeroen Bosch Ziekenhuis
Cardiology
's-Hertogenbosch, Netherlands
Noordwest Ziekenhuisgroep Stichting
Cardiology
Alkmaar, Netherlands
Amsterdam UMC Stichting
Cardiology
Amstelveen, Netherlands
Sponsor: Stichting Rijnstate Ziekenhuis
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.