Atrial Fibrillation: Stopping Anticoagulants After Heart Surgery

We are studying whether patients with atrial fibrillation can safely stop anticoagulant therapy after undergoing surgical left atrial appendage closure. This trial looks at the risks of stroke and bleeding in these patients.

>2 yearsMonitoring phase (IV)No PlaceboCost ReimbursementStandard MedicinesOralCardiologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Apixaban
Apixaban is a medicine that helps prevent dangerous blood clots and reduces the risk of stroke in people with an irregular heart rhythm.
Edoxaban
Edoxaban is a medicine that thins the blood to help prevent strokes in people with irregular heartbeat and treat or prevent harmful blood clots.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Apixaban
Apixaban is a substance that helps prevent harmful blood clots and lowers stroke risk in people with irregular heart rhythm.
Dabigatran
Dabigatran is a substance that helps prevent and treat blood clots by reducing the blood's ability to form clots.
Edoxaban
Edoxaban is a substance that helps prevent harmful blood clots and lowers stroke risk in people with an irregular heartbeat.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abatixent
Abidalo
Aboxoma

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Aalborg University Hospital
Dept. of Cardiothoracic and Vascular Surgery
Aalborg, Denmark
Aarhus Universitetshospital
Dept. of Cardiothoracic and Vascular Surgery
Århus, Denmark
Gentofte Hospital
Dept. of Cardiology
Charlottenlund, Denmark
Sponsor: Odense University Hospital
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.