Axial Spondyloarthritis: NSAIDs vs. Biosimilar TNF Blockers

We are comparing the effectiveness of high-dose NSAIDs and a biosimilar TNF blocker for patients with axial spondyloarthritis who haven't responded to NSAIDs. The study will also look at side effects and inflammation levels.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Acemetacin Heumann
Acemetacin Heumann is a pain-relieving and anti-inflammatory medicine used to treat arthritis and other inflammatory conditions.
Acemetacin Stada
Acemetacin Stada is a painkiller used to relieve pain and swelling from arthritis and other types of inflammation.
Celecoxib
Celecoxib is a medicine used to reduce pain and swelling from arthritis and other short-term painful conditions.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Acemetacin
Acemetacin is a substance that reduces pain and inflammation, commonly used for arthritis and musculoskeletal pain.
Celecoxib
Celecoxib is a substance that reduces pain and inflammation, commonly used to treat arthritis and other inflammatory conditions.
Diclofenac
Diclofenac is a substance that reduces pain and inflammation from conditions like arthritis and injuries.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

200 Mg + 500 Mg
3 Months Ibuprofen Strawberry Flavour
3 Months Plus Strawberry Flavour

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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St. Elisabeth Gruppe GmbH Katholische Kliniken Rhein-Ruhr
Rheumazentrum Ruhrgebiet
Herne, Germany
Sponsor: St. Elisabeth Gruppe GmbH Katholische Kliniken Rhein-Ruhr
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.