Bacterial Brain Abscess: Oral vs. IV Antibiotics

We are studying whether oral antibiotics are as effective as IV antibiotics for treating bacterial brain abscesses. This trial will help us understand the best treatment options and their impact on recovery and quality of life.

>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesOralInjectionInfectious DiseasesNeurology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cefotaxime Mip
Cefotaxime Mip is an antibiotic medicine used to treat serious bacterial infections.
Ceftriaxone Arrow
Ceftriaxone Arrow is an antibiotic medicine used to treat a range of serious bacterial infections.
Flagyl
Flagyl is an antibiotic medicine used to treat certain bacterial and parasitic infections in the stomach, reproductive organs, and other parts of the body.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Amoxicillin
Amoxicillin is an antibiotic substance used to treat a range of common bacterial infections such as ear, throat, and urinary tract infections.
Cefotaxime
Cefotaxime is an antibiotic substance used to treat serious bacterial infections by stopping bacteria from growing.
Ceftriaxone Sodium
Ceftriaxone sodium is an antibiotic substance used to treat many serious bacterial infections, including pneumonia, bloodstream infections, and meningitis.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abimox
Abiox
Acea

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Aalborg University Hospital
Department of Infectious Diseases
Aalborg, Denmark
Aarhus Universitetshospital
Department of Infectious Diseases
Århus, Denmark
Rigshospitalet
Department of Infectious Diseases
Copenhagen, Denmark
Sponsor: Aalborg University Hospital
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.