Breast Cancer: Lower Dose of CDK 4/6-Inhibitors

We are studying whether a lower initial dose of a cancer medication is effective for older breast cancer patients compared to the standard dose. This trial aims to improve treatment outcomes and quality of life for vulnerable patients.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Arimidex
Arimidex is a medicine used to treat certain types of breast cancer in postmenopausal women by lowering estrogen.
Aromasin
Aromasin is a medicine used to treat certain types of breast cancer in postmenopausal women by reducing the body’s estrogen levels.
Faslodex
Faslodex is a medicine used to treat advanced breast cancer by blocking hormones that help the cancer grow.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Abemaciclib
Abemaciclib is a substance that slows growth of certain breast cancer cells by blocking proteins that help them divide.
Anastrozole
Anastrozole is a substance that lowers estrogen levels to help treat and prevent hormone-sensitive breast cancer in postmenopausal women.
Exemestane
Exemestane is a substance that lowers estrogen levels to help treat hormone-sensitive breast cancer in postmenopausal women.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adiunastrol
Afultrant
Agerdex

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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HUS Helsinki University Hospital
Department of Oncology, Comprehensive Cancer Center
Helsinki, Finland
“Attikon” University General Hospital of Athens
2nd Propaedeutic Clinic of Internal Medicine, Oncology Unit
Chaïdári, Greece
HYGEIA Hospital
Second Department of Medical Oncology
Filothéi, Greece

Sponsor: Region Oerebro Laen
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.