Breast Reconstruction: Goal-Directed Fluid Therapy

We are studying how a specific fluid management approach during DIEP breast reconstruction may reduce swelling and improve healing. This trial aims to see if it helps with better blood flow to the surgical area.

>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesInjectionGynecology and ObstetricsInternal MedicineOtolaryngology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Plasma-Lyte® 148 (Ph 7.4)
Plasma-Lyte 148 is an intravenous fluid used to restore body fluids and salts during dehydration, surgery, or medical emergencies.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Magnesium Chloride Hexahydrate
Magnesium chloride hexahydrate is a magnesium supplement used to restore low magnesium levels and support healthy muscle and nerve function.
Noradrenaline Hydrochloride
Noradrenaline hydrochloride is a substance that raises blood pressure by narrowing blood vessels and supporting heart function in severe low blood pressure or shock.
Noradrenaline Tartrate
Noradrenaline tartrate is a substance that raises blood pressure by constricting blood vessels and supporting heart function during severe low-blood-pressure situations.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Addex
Aminomel
Aminomix 1 Novum

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Az Maria Middelares Gent
Anaesthesiology
Gent, Belgium
Sponsor: Az Maria Middelares Gent
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.