Cholangiocarcinoma: Comparing RFA and PDT Treatments

We are studying whether radiofrequency ablation or photodynamic therapy helps patients with cholangiocarcinoma live longer. We’ll also look at how these treatments affect quality of life and any potential side effects.

>2 years ≤5 visits Monitoring phase (IV)No Placebo Partially Remote Standard Medicines InjectionGastroenterologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Foscan

Foscan is a medicine used with light-based therapy to treat certain head and neck cancers.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Porfimer Sodium

Porfimer sodium is a substance that makes cancerous or abnormal cells sensitive to light so targeted light treatment can destroy them.

Temoporfin

Temoporfin is a photosensitizing substance used in photodynamic therapy to help destroy certain cancers by activating with light.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Vivantes Netzwerk fuer Gesundheit GmbH

Innere Medizin-Gastroenterologie

Berlin, Germany

Universitaetsklinikum Bonn AöR

Medizinische Klinik und Poliklinik I

Bonn, Germany

Goethe University Frankfurt

Universitätsklinikum Frankfurt, Medizinische Klinik 1

Frankfurt am Main, Germany

Sponsor: University Of Leipzig

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.