Chronic Hepatitis D: Bulevirtide Treatment Study

We are studying the effects of Bulevirtide in patients with chronic hepatitis D to see how well it reduces the virus and improves liver health. This research will help us understand the treatment's safety and effectiveness over time.

Confirmation phase (III)Monitoring phase (IV)No PlaceboStandard MedicinesOralInjectionHepatologyInfectious Diseases

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Baraclude
Baraclude is a medicine used to treat chronic hepatitis B by helping lower the amount of virus in the body and protect the liver.
Hepcludex
Hepcludex is a medicine used to treat chronic hepatitis D, a viral infection of the liver.
Pegasys
Pegasys is a medicine used to treat hepatitis B and C by helping the body fight the viral infection.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bulevirtide
Bulevirtide is a substance that prevents hepatitis B and D viruses from entering liver cells to help manage chronic hepatitis D.
Entecavir
Entecavir is an antiviral substance used to treat chronic hepatitis B by stopping the hepatitis B virus from multiplying.
Peginterferon Alfa-2a
Peginterferon Alfa-2a is a substance that stimulates the immune system to help treat chronic hepatitis C and other viral infections.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Agardon
Edevira
Entecavir Accord

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Karolinska University Hospital
Department of Infectious Diseases
Huddinge, Sweden
Sponsor: Karolinska University Hospital
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.