Chronic Lymphocytic Leukemia: Acalabrutinib Treatment Study

We are investigating whether acalabrutinib is safe and effective for adults with chronic lymphocytic leukemia and heart problems. This study compares it to other treatment options available for these patients.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Calquence
Calquence is a cancer medicine used to treat certain blood cancers, such as chronic lymphocytic leukemia and mantle cell lymphoma.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Acalabrutinib
Acalabrutinib is a substance that blocks a protein in B cells to treat certain B‑cell blood cancers.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Fakultni Nemocnice Brno
Interni hematologicka a onkologicka klinika
Brno, Czechia
Fakultni Nemocnice Hradec Kralove
IV. Interni hematologicka klinika
Hradec Králové, Czechia
Fakultni Nemocnice Kralovske Vinohrady
Hematologická klinika
Prague, Czechia

Sponsor: AstraZeneca AB
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.