Chronic Pelvic Pain: Esketamine Infusion Study

We are investigating whether an 8-hour infusion of esketamine can help reduce chronic pelvic pain in individuals with endometriosis. The study also examines treatment experiences and overall quality of life.

Monitoring phase (IV)Standard MedicinesOralInjectionGynecology and ObstetricsPsychiatry

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Ketanest S
Ketanest S is an anesthetic medicine used to put patients to sleep and relieve pain during surgeries and medical procedures.
Ondansetron
Ondansetron is a medicine that helps prevent nausea and vomiting after surgery or during cancer treatment.
Ondansetron Morningside Healthcare
Ondansetron Morningside Healthcare is a medicine used to prevent nausea and vomiting caused by chemotherapy, radiation, or surgery.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Esketamine
Esketamine is a fast-acting antidepressant substance used to relieve depression symptoms when other treatments haven't worked.
Esketamine Hydrochloride
Esketamine hydrochloride is a fast-acting substance used to treat severe depression when other treatments haven’t worked.
Ondansetron
Ondansetron is a substance that prevents nausea and vomiting, especially related to chemotherapy, radiation therapy, or after surgery.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Atossa
Atossa
Avessaron

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Reinier de Graaf Groep
NEK
Delft, Netherlands
Sponsor: Reinier de Graaf Groep
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.