COPD Exacerbation: New Diagnostic Strategy

We are testing a new method using advanced diagnostics to see if it can help reduce antibiotic use during severe COPD flare-ups. This study compares this approach to standard treatment to evaluate its effectiveness and safety.

>2 yearsConfirmation phase (III)Monitoring phase (IV)No PlaceboStandard MedicinesOralInjectionPulmonology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cefotax
Cefotax is an antibiotic medicine used to treat serious bacterial infections such as pneumonia, bloodstream infections, and meningitis.
Spiramycine Eg
Spiramycine Eg is an antibiotic medicine used to treat certain bacterial infections.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Amoxicillin
Amoxicillin is an antibiotic substance used to treat a range of common bacterial infections such as ear, throat, and urinary tract infections.
Cefotaxime
Cefotaxime is an antibiotic substance used to treat serious bacterial infections by stopping bacteria from growing.
Ciprofloxacin
Ciprofloxacin is an antibiotic used to treat various bacterial infections, such as urinary, respiratory, and skin infections.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Antadar I.M.
Antadar I.V.
Biotaksym

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hopital Tenon
Réanimation et USC Médico-chirurgicale
Bagnolet, France
University Hospital Of Clermont-Ferrand
Service de Médecine Intensive et Réanimation
Beaumont, France
Centre Hospitalier Universitaire Reims
Médecine Intensive et Réanimation polyvalente
Cormontreuil, France
Sponsor: Assistance Publique Hopitaux De Paris
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.