Coronary Artery Disease: Comparing Diabetes Medications

We are studying how well a new diabetes medication works to improve heart health in people with coronary artery disease and prediabetes. This trial compares a GLP-1 agonist and an SGLT-2 inhibitor to standard treatment.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Formetic
Forxiga
Forxiga is a medicine that lowers blood sugar in adults with type 2 diabetes and can also help certain heart and kidney conditions.
Rybelsus
Rybelsus is a medicine taken by mouth to help lower blood sugar in adults with type 2 diabetes.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dapagliflozin
Dapagliflozin is a substance that helps lower blood sugar in people with type 2 diabetes by causing the kidneys to remove excess glucose in urine.
Metformin Hydrochloride
Metformin hydrochloride is a substance that helps lower blood sugar in people with type 2 diabetes.
Semaglutide
Semaglutide is a substance that helps lower blood sugar in people with type 2 diabetes and can also reduce appetite to aid weight loss.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abmetfina Xr
Adimet
Adimet Xr

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy
Klinika Choroby Wieńcowej i Strukturalnych Chorób Serca, Oddział kliniczny
Wawer, Poland
Sponsor: Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.