Crohn's and Colitis: Stopping Anti-TNF Treatment

We are studying if specific markers can help identify patients who can safely stop their anti-TNF treatment while in remission. This may help tailor treatment plans for better health outcomes.

>2 years≤5 visitsMonitoring phase (IV)No PlaceboPartially RemoteStandard MedicinesInjectionGastroenterologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Humira
Humira is a medicine that reduces inflammation by calming the immune system to treat autoimmune conditions such as arthritis and Crohn’s disease.
Inflectra
Inflectra is a medicine given by infusion to treat autoimmune conditions like rheumatoid arthritis, Crohn’s disease, ulcerative colitis, and certain types of psoriasis.
Remicade
Remicade is a medicine used to reduce inflammation and control autoimmune conditions like rheumatoid arthritis and inflammatory bowel disease.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Adalimumab
Adalimumab is a biologic that blocks a key inflammatory protein (TNF) to reduce inflammation in autoimmune conditions like rheumatoid arthritis and Crohn's disease.
Infliximab
Infliximab is a substance that reduces inflammation by blocking a protein called TNF and is used for autoimmune conditions like rheumatoid arthritis and Crohn's.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Amgevita
Amsparity
Flixabi

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Region Skane Skanes Universitetssjukhus
Mag- och tarmmottagning Malmö, Jan Waldenströms gata 14, 20502 Malmö
Dalby, Sweden
Region Skane Kristianstad Central Hospital
Medicinkliniken, CSK
Kristianstad, Sweden
Region Oestergoetland
Magtarmmedicinska kliniken
Linköping, Sweden
Sponsor: Region Skane
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.