Cytisine vs. Nicotine Replacement Therapy for Smokers with Chronic Kidney Disease

We are studying whether cytisine can help nicotine-dependent patients with chronic kidney disease quit smoking more effectively than traditional nicotine replacement therapy. This trial will also look at any side effects from both treatments.

Monitoring phase (IV)No Placebo Standard Medicines OralNephrologyPsychiatry

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Desmoxan

Desmoxan is a medicine used to help people quit smoking by reducing cravings and withdrawal symptoms.

Nicorette Coolmint

Nicorette Coolmint is a nicotine gum used to help people stop smoking by reducing cravings and withdrawal symptoms.

Nicorette Fruit

Nicorette Fruit is a flavored gum that helps people stop smoking by easing cravings and withdrawal symptoms.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cytisinicline

Cytisinicline is a substance that helps people stop smoking by reducing nicotine cravings and easing withdrawal symptoms.

Nicotine

Nicotine is a stimulant that affects the nervous system and is used to help people quit smoking.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Asmoken

Belnifrem

Boots Nicassist

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Uniwersyteckie Centrum Kliniczne Warszawskiego Uniwersytetu Medycznego

Klinika Medycyny Transplantacyjnej, Nefrologii i Chorób Wewnętrznych

Warsaw, Poland

Sponsor: Narodowy Instytut Onkologii Im. Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.