Dementia: New Treatments for Agitation

We are exploring whether certain psychotropic medications can help reduce agitation in dementia patients who haven't responded to standard treatments. The study also examines potential side effects and personalized treatment methods.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Lorazepam
Lorazepam is a medicine used to relieve anxiety and calm people for short-term sleep or before medical procedures.
Quetiapine
Quetiapine is a medicine used to treat schizophrenia and bipolar disorder by helping control mood swings and symptoms like hallucinations.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Lorazepam
Lorazepam is a substance that reduces anxiety and produces calming, sedative effects to ease panic, severe agitation, or help with sleep.
Olanzapine
Olanzapine is a substance used to treat schizophrenia and bipolar disorder by helping reduce psychotic symptoms and stabilize mood.
Pregabalin
Pregabalin is a substance that eases nerve-related pain and is used to treat certain seizures and anxiety.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Quetiapine
Olanzapine
Lorazepam

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Akivass
Alaquet Xl
Anaquetan Xr

Sponsor: Amsterdam UMC
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.