Denosumab: Impact on Muscle Strength and Insulin Sensitivity

We are studying whether denosumab can improve muscle strength and insulin sensitivity in participants. This trial compares its effects to a placebo to understand its potential benefits.

6-12 months Monitoring phase (IV)Standard Medicines InjectionEndocrinologyHepatologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Saline

Saline is a sterile saltwater solution used to hydrate patients, replace lost fluids, and rinse wounds or medical equipment.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Denosumab

Denosumab is a substance that helps prevent bone breakdown and strengthen bones to reduce fracture risk in osteoporosis and cancer-related bone loss.

Sodium Chloride

Sodium chloride is a substance used to replace salts and fluids in the body and to clean or irrigate wounds and nasal passages.

Sodium Chloride Solution 0.9%

Sodium chloride 0.9% is a sterile salt solution used to replace fluids and electrolytes, hydrate patients, and clean wounds or body cavities.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acuolens

Addex Natriumklorid

Aminoplasmal E

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Region Midtjylland

Dept. of Endocrinology and Internal Medicine

Århus, Denmark

Sponsor: Region Midtjylland

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.