End-of-Life Care: Midazolam and Morphine Study

We are investigating how midazolam and morphine can help relieve pain and discomfort in elderly patients during their final days. This study aims to understand the best dosing strategies and any potential side effects.

1-2 years Monitoring phase (IV)No Placebo Standard Medicines InjectionGastroenterologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Midazolam

Midazolam is a medicine used to calm and sedate people for medical procedures and to help control serious seizures.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dobutamine Hydrochloride

Dobutamine hydrochloride is a substance that strengthens heart pumping to improve blood flow in people with severe heart failure or shock.

Midazolam

Midazolam is a substance that produces sedation and reduces anxiety, often used to calm patients before procedures or help control seizures.

Morphine

Morphine is a substance that relieves severe pain by blocking pain signals in the brain and nervous system.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Buccolam

Dormicum

Dormicum V

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Leuven

Geriatric Medicine

Heverlee, Belgium

Universitair Ziekenhuis Gent

Geriatric Medicine

Ledeberg, Belgium

Sponsor: UZ Leuven

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.