Febrile Neutropenia: SAFE Study on Short Antibiotic Treatment

We are studying whether stopping antibiotics after 3 days is as safe as continuing them longer for patients with febrile neutropenia. This research aims to find a potentially safer treatment approach for hematology patients.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cefepime Tzf
Cefepime Tzf is an antibiotic medicine used to treat serious bacterial infections, often in hospitals.
Ceftazidime Kabi
Ceftazidime Kabi is an antibiotic medicine used to treat serious bacterial infections, often given by injection in hospitals.
Imipenem/Cilastatin
Imipenem/cilastatin is an antibiotic medicine used to treat serious bacterial infections.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cefepime
Cefepime is an antibiotic used to treat serious bacterial infections such as severe pneumonia and bloodstream infections.
Ceftazidime
Ceftazidime is an antibiotic substance used to treat serious bacterial infections, particularly those caused by gram-negative bacteria.
Ceftazidime Pentahydrate
Ceftazidime pentahydrate is an antibiotic substance used to treat serious bacterial infections, especially those caused by Gram-negative bacteria like Pseudomonas.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Agenor
Agenorem
Alphacef

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Vrije Universiteit Brussel
Hematology
Etterbeek, Belgium
Grand Hopital De Charleroi
Hematology
Gilly, Belgium
UZ Leuven
Hematology
Heverlee, Belgium

Sponsor: UZ Leuven
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.