Fertility Treatment: Progesterone Support in IUI

We are studying if adding progesterone support helps couples with unexplained infertility achieve higher live birth rates during intra-uterine insemination. We also want to see if this approach is cost-effective and safe.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Lipanthyl Micronised
Lipanthyl Micronised is a medicine used to lower high cholesterol and triglyceride levels to help reduce the risk of heart disease.
Utrogestan® Vaginal
Utrogestan Vaginal is a hormone medicine inserted vaginally to help support early pregnancy and assist fertility treatments.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Fenofibrate Micronised
Fenofibrate micronised is a substance that lowers high triglycerides and cholesterol levels in the blood.
Micronised
Progesterone
Progesterone is a hormone that helps regulate the menstrual cycle and supports pregnancy.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Placebo

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Biofibrat
Catalip Micronizado
Crinone

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Jeroen Bosch Ziekenhuis
Reproductive medicine and gynecology
's-Hertogenbosch, Netherlands
Stichting Flevoziekenhuis
Reproductive medicine and gynecology
Almere Stad, Netherlands
Amsterdam UMC
Reproductive Medicine and Gynaecology
Amstelveen, Netherlands

Sponsor: University Medical Center Utrecht
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.