Fludarabine in Stem Cell Transplantation

We are studying how Fludarabine exposure varies among patients receiving reduced intensity stem cell transplants. The goal is to understand its effects on long-term health and potential side effects.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Fludarabine Teva
Fludarabine Teva is a chemotherapy medicine used to treat certain blood cancers, such as chronic lymphocytic leukemia.
Thymoglobuline
Thymoglobuline is a medicine used to prevent and treat organ transplant rejection by reducing the body's immune response.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Anti-T Lymphocyte Immunoglobulin For Human Use
Anti-T lymphocyte immunoglobulin is a preparation of antibodies that reduces activity of immune T cells to prevent or treat organ transplant rejection.
Fludarabine Phosphate
Fludarabine phosphate is used to treat certain blood cancers, especially chronic lymphocytic leukemia and some lymphomas.
Melphalan
Melphalan is a substance used to treat certain cancers by killing or stopping the growth of cancer cells.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Fludarabine
Grafalon
Alkeran

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Bendarabin
Beneflur
Fludara

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Universitair Ziekenhuis Gent
Hematology
Ledeberg, Belgium
Az St-Jan Brugge-Oostende A.V.
Hematology
Sint-Andries, Belgium
CHU De Liege
Hematology
Tilff, Belgium
Sponsor: Universitair Ziekenhuis Gent
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.